Water → 5-(5-Bromo-2-chloropyrimidin-4-yl)-N-methyl-N-phenylthiazol-2-amine
Reaction equation
[Br:19][c:20]1[cH:21][n:22][c:23]([Cl:26])[n:24][cH:25]1.[C:1]([Li:2])([CH3:3])([CH3:4])[CH3:5].[CH2:47]1[O:48][CH2:49][CH2:50][CH2:51]1.[CH3:41][CH2:42][O:43][CH2:44][CH3:45].[CH3:6][N:7]([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[c:14]1[s:15][cH:16][cH:17][n:18]1.[Cl:27][C:28]1=[C:39]([Cl:40])[C:37](=[O:38])[C:34]([C:35]#[N:36])=[C:31]([C:32]#[N:33])[C:29]1=[O:30].[OH2:46]>>[CH3:6][N:7]([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[c:14]1[s:15][c:16](-[c:21]2[c:20]([Br:19])[cH:25][n:24][c:23]([Cl:26])[n:22]2)[cH:17][n:18]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-05fdfafff6c4402ba3e78b8cc5b91f25
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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