Acetone → 1-Benzyl-6-(benzyloxy)-N-(3,4-difluorobenzyl)-2-isopropyl-1H-indole-3-carboxamide
Reaction equation
[Br:39][CH2:40][c:41]1[cH:42][cH:43][cH:44][cH:45][cH:46]1.[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9]([CH:30]([CH3:31])[CH3:32])[c:10]([C:18](=[O:19])[NH:20][CH2:21][c:22]2[cH:23][c:24]([F:29])[c:25]([F:28])[cH:26][cH:27]2)[c:11]2[cH:12][cH:13][c:14]([OH:17])[cH:15][c:16]12.[CH3:54][C:55](=[O:56])[CH3:57].[I-:47].[K+:33].[K+:34].[Na+:48].[O-:35][C:36]([O-:37])=[O:38].[O:49]=[CH:50][N:51]([CH3:52])[CH3:53]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9]([CH:30]([CH3:31])[CH3:32])[c:10]([C:18](=[O:19])[NH:20][CH2:21][c:22]2[cH:23][c:24]([F:29])[c:25]([F:28])[cH:26][cH:27]2)[c:11]2[cH:12][cH:13][c:14]([O:17][CH2:40][c:41]3[cH:42][cH:43][cH:44][cH:45][cH:46]3)[cH:15][c:16]12Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-38c56817e1bc4ba795f8e426d75630eb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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