Hydrochloric Acid → (3aRS,7aRS)-7,7-bis(3-fluorophenyl)-2-[(2-dimethylaminophenyl)acetyl]perhydro-4-isoindolone
Reaction equation
[CH3:1][N:2]([c:3]1[c:4]([CH2:9][C:10](=[O:11])[OH:12])[cH:5][cH:6][cH:7][cH:8]1)[CH3:13].[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[Cl:46][CH2:47][Cl:48].[ClH:14].[F:15][c:16]1[cH:17][c:18]([C:22]2([c:32]3[cH:33][c:34]([F:38])[cH:35][cH:36][cH:37]3)[CH2:23][CH2:24][C:25](=[O:31])[CH:26]3[CH2:27][NH:28][CH2:29][CH:30]23)[cH:19][cH:20][cH:21]1>>[CH3:1][N:2]([c:3]1[c:4]([CH2:9][C:10](=[O:12])[N:28]2[CH2:27][CH:26]3[C:25](=[O:31])[CH2:24][CH2:23][C:22]([c:18]4[cH:17][c:16]([F:15])[cH:21][cH:20][cH:19]4)([c:32]4[cH:33][c:34]([F:38])[cH:35][cH:36][cH:37]4)[CH:30]3[CH2:29]2)[cH:5][cH:6][cH:7][cH:8]1)[CH3:13]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-6b24ce4fe95a46d6aa5ac1420b4aeb55
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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