Sodium ion → Tert-butyl 8-amino-1-benzyl-1,2,3,4-tetrahydro-2-oxoquinolin-3-ylcarbamate

HRID 663451Notes

Reaction equation

HRID 663451 reaction equation
[Br:23][CH2:24][c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1.[CH3:31][N:32]([CH3:33])[CH:34]=[O:35].[H-:21].[NH2:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:11]1[NH:10][C:9](=[O:12])[CH:8]([NH:13][C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20])[CH2:7]2.[Na+:22]>>[NH2:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:11]1[N:10]([CH2:24][c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1)[C:9](=[O:12])[CH:8]([NH:13][C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20])[CH2:7]2

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 7498Benzyl BromideHCID 166653HydrideHCID 59620337Tert-butyl 8-amino-2-oxo-1,2,3,4-tetrahydroquinolin-3-ylcarbamate

Product 1

HCID 59620406Tert-butyl 8-amino-1-benzyl-1,2,3,4-tetrahydro-2-oxoquinolin-3-ylcarbamate

Sources & evidence

ORD record
ord-89e5cd3962bb4207b413d1c3ff700108
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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