反应详情

温度

85 °C

A stirred mixture of 23.8 g of 4-cyclopropyl-4-tri-methylsiloxy-1-octyne (Example 10), 28 ml of tri-n-butyltin hydride, and 50 mg of azobisisobutyronitrile under nitrogen is heated to 85° C. After the resulting exothermic reaction subsides the mixture is heated at 130° C for 1 hour. The crude product is evaporatively distilled to give a liquid, p.m.r. spectrum (C D Cl3): δ0.10 (trimethylsiloxy group), 2.33 (doublet, =CHCH2), and 6.02 (vinyl hydrogens).

1. customAfter the resulting exothermic reaction
2. temperatureis heated at 130° C for 1 hour
3. distillationThe crude product is evaporatively distilled
4. customto give a liquid, p.m.r