Dichloromethane → 4-Chloro-6-ethyl-5-fluoropyrimidine

HRID 664253Notes

Reaction equation

HRID 664253 reaction equation
[CH2:1]([CH3:2])[c:3]1[c:4]([F:10])[c:5]([OH:9])[n:6][cH:7][n:8]1.[CH3:19][CH2:20][N:21]([CH2:22][CH3:23])[CH2:24][CH3:25].[Cl:11][CH2:12][Cl:13].[P:14]([Cl:15])([Cl:16])([Cl:17])=[O:18]>>[CH2:1]([CH3:2])[c:3]1[c:4]([F:10])[c:5]([Cl:11])[n:6][cH:7][n:8]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 24813Phosphorus oxychlorideHCID 178437743HCID 178437743, compound

Product 1

HCID 167434454-Chloro-6-ethyl-5-fluoropyrimidine

Sources & evidence

ORD record
ord-0db9fc64cf874b7e98aa830e1c8092e2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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