Dichloromethane → 3-(2'-amino-2-phenyl-5'H-spiro[chroman-4,4'-thiazole]-6-yl)benzonitrile
Reaction equation
[CH:31]([N:32]([CH2:33][CH3:34])[CH:35]([CH3:36])[CH3:37])([CH3:38])[CH3:39].[Cl:53][CH2:54][Cl:55].[F:40][C:41]([F:42])([F:43])[C:44]([O:45][C:46](=[O:47])[C:48]([F:49])([F:50])[F:51])=[O:52].[NH2:1][C:2]1=[N:30][C:5]2([CH2:4][S:3]1)[CH2:6][CH:7]([c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1)[O:8][c:9]1[cH:10][cH:11][c:12](-[c:15]3[cH:16][c:17]([C:18](=[O:19])[NH2:20])[cH:21][cH:22][cH:23]3)[cH:13][c:14]12>>[NH2:1][C:2]1=[N:30][C:5]2([CH2:4][S:3]1)[CH2:6][CH:7]([c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1)[O:8][c:9]1[cH:10][cH:11][c:12](-[c:15]3[cH:16][c:17]([C:18]#[N:20])[cH:21][cH:22][cH:23]3)[cH:13][c:14]12Participants
5
Sources & evidence
- ORD record
- ord-8d0457ddbb82467ea90b2f7e06fad8c1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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