Ammonium → 1-[2-[2-Bromo-5-(difluoromethoxy)-4-methoxyphenyl]acetyl]-2-(4-fluorophenyl)-2,3-dihydropyridin-4-one
Reaction equation
[Br:21][c:22]1[c:23]([CH2:34][C:35](=[O:36])[OH:37])[cH:24][c:25]([O:30][CH:31]([F:32])[F:33])[c:26]([O:28][CH3:29])[cH:27]1.[CH2:15]([Li:16])[CH2:17][CH2:18][CH3:19].[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[Cl-:20].[Cl-:38].[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[NH:9][CH:10]=[CH:11][C:12](=[O:14])[CH2:13]2)[cH:6][cH:7]1.[NH4+:39]>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[N:9]([C:35]([CH2:34][c:23]3[c:22]([Br:21])[cH:27][c:26]([O:28][CH3:29])[c:25]([O:30][CH:31]([F:32])[F:33])[cH:24]3)=[O:36])[CH:10]=[CH:11][C:12](=[O:14])[CH2:13]2)[cH:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-3291836823124f998ba8e7456b05d35c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…