Acetate → 2-(3-Phenyl-propyl)-6-(3,3-diacetoxy-1-propen-1-yl)-1-oxo-1,2,3,4-tetrahydroisoquinoline

HRID 664418Notes

Reaction equation

HRID 664418 reaction equation
[C:25]([CH3:26])(=[O:27])[O:28][CH:29]([CH:30]=[CH2:31])[O:32][C:33]([CH3:34])=[O:35].[CH3:22][C:23]#[N:24].[CH3:36][CH2:37][N:38]([CH2:39][CH3:40])[CH2:41][CH3:42].[CH3:43][CH2:44][O:45][C:46]([CH3:47])=[O:48].[O-:50][C:51]([CH3:52])=[O:53].[O-:54][C:55]([CH3:56])=[O:57].[Pd+2:49].[c:1]1([CH2:7][CH2:8][CH2:9][N:10]2[C:11](=[O:21])[c:12]3[cH:13][cH:14][c:15]([Br:20])[cH:16][c:17]3[CH2:18][CH2:19]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH2:7][CH2:8][CH2:9][N:10]2[C:11](=[O:21])[c:12]3[cH:13][cH:14][c:15]([CH:31]=[CH:30][CH:29]([O:28][C:25]([CH3:26])=[O:27])[O:32][C:33]([CH3:34])=[O:35])[cH:16][c:17]3[CH2:18][CH2:19]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 6342AcetonitrileHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 612263,3-DiacetoxypropeneHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 189639072-(3-Phenylpropyl)-6-bromo-1-oxo-1,2,3,4-tetrahydroisoquinoline

Product 1

HCID 543550622-(3-Phenyl-propyl)-6-(3,3-diacetoxy-1-propen-1-yl)-1-oxo-1,2,3,4-tetrahydroisoquinoline

Sources & evidence

ORD record
ord-fe842316140249189a55ed2099cba231
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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