Dimethylformamide → 1-Benzyl-4-thiophen-3-yl-piperidine-3-carbonyl chloride
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([C:19](=[O:20])[OH:21])[CH:11]([c:14]2[cH:15][s:16][cH:17][cH:18]2)[CH2:12][CH2:13]1.[Cl:27][C:28]([C:29]([Cl:30])=[O:31])=[O:32].[Cl:33][CH2:34][Cl:35].[O:22]=[CH:23][N:24]([CH3:25])[CH3:26]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([C:19](=[O:21])[Cl:27])[CH:11]([c:14]2[cH:15][s:16][cH:17][cH:18]2)[CH2:12][CH2:13]1Participants
5
Sources & evidence
- ORD record
- ord-9d3ec074c29b41de93b66f0c468f31e5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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