Dichloromethane → N'-{2-[5-(4-Bromo-phenyl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-N'-isopropyl-hydrazine-carboxylic acid methyl ester

HRID 664562Notes

Reaction equation

HRID 664562 reaction equation
[Br:31][c:32]1[cH:33][cH:34][c:35](-[c:38]2[cH:39][n:40][c:41]([CH:43]3[NH:44][CH2:45][CH2:46][CH2:47]3)[nH:42]2)[cH:36][cH:37]1.[CH3:13][O:14][C:15](=[O:16])[NH:17][NH:18][CH:19]([CH3:20])[CH3:21].[CH:22]([N:23]([CH2:24][CH3:25])[CH:26]([CH3:27])[CH3:28])([CH3:29])[CH3:30].[Cl:1][C:2]([Cl:3])([O:4][C:5]([O:6][C:7]([Cl:8])([Cl:9])[Cl:10])=[O:11])[Cl:12].[Cl:48][CH2:49][Cl:50]>>[C:5](=[O:11])([N:18]([NH:17][C:15]([O:14][CH3:13])=[O:16])[CH:19]([CH3:20])[CH3:21])[N:44]1[CH:43]([c:41]2[n:40][cH:39][c:38](-[c:35]3[cH:34][cH:33][c:32]([Br:31])[cH:37][cH:36]3)[nH:42]2)[CH2:47][CH2:46][CH2:45]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 81531DiisopropylethylamineHCID 94429TriphosgeneHCID 436506945-(4-Bromo-phenyl)-2-pyrrolidin-2-yl-1H-imidazoleHCID 57863323Methyl 2-isopropylhydrazinecarboxylate

Product 1

HCID 66621058N'-{2-[5-(4-Bromo-phenyl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-N'-isopropyl-hydrazine-carboxylic acid methyl ester

Sources & evidence

ORD record
ord-b35d93f197614ab9998b359c1600c52f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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