Dimethylformamide → tert-Butyl 4-((2-chloropyrimidin-4-yl)amino)piperidine-1-carboxylate

HRID 664749Notes

Reaction equation

HRID 664749 reaction equation
[C:9]([CH3:10])([CH3:11])([CH3:12])[O:13][C:14](=[O:15])[N:16]1[CH2:17][CH2:18][CH:19]([NH2:22])[CH2:20][CH2:21]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([Cl:8])[n:7]1.[O:23]=[CH:24][N:25]([CH3:26])[CH3:27]>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([NH:22][CH:19]2[CH2:18][CH2:17][N:16]([C:14]([O:13][C:9]([CH3:10])([CH3:11])[CH3:12])=[O:15])[CH2:21][CH2:20]2)[n:7]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 775312,4-DichloropyrimidineHCID 12682914-Amino-1-Boc-piperidine

Product 1

HCID 22309647tert-Butyl 4-((2-chloropyrimidin-4-yl)amino)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-5c285fded0ac419a8df7261472d6ddb1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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