Hydrochloric Acid → 6-[1-(N,N-Dimethylsulfamoyl)piperidin-4-yloxy]-4-(3-chloro-2-fluoroanilino)-7-methoxyquinazoline
Reaction equation
[CH2:47]([Cl:48])[Cl:49].[CH3:1][N:2]([S:3](=[O:4])(=[O:5])[Cl:6])[CH3:7].[CH:38]([N:39]([CH:40]([CH3:41])[CH3:42])[CH2:43][CH3:44])([CH3:45])[CH3:46].[ClH:8].[ClH:9].[NH:10]1[CH2:11][CH2:12][CH:13]([O:16][c:17]2[cH:18][c:19]3[c:20]([NH:29][c:30]4[c:31]([F:37])[c:32]([Cl:36])[cH:33][cH:34][cH:35]4)[n:21][cH:22][n:23][c:24]3[cH:25][c:26]2[O:27][CH3:28])[CH2:14][CH2:15]1>>[CH3:1][N:2]([S:3](=[O:4])(=[O:5])[N:10]1[CH2:11][CH2:12][CH:13]([O:16][c:17]2[cH:18][c:19]3[c:20]([NH:29][c:30]4[c:31]([F:37])[c:32]([Cl:36])[cH:33][cH:34][cH:35]4)[n:21][cH:22][n:23][c:24]3[cH:25][c:26]2[O:27][CH3:28])[CH2:14][CH2:15]1)[CH3:7]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-ced6d69530914868b73c9c92a53f339d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…