Dichloromethane → 2-(6-(Trifluoromethyl)pyridin-2-yl)acetic acid

HRID 665082Notes

Reaction equation

HRID 665082 reaction equation
[CH2:19]([SiH:20]([CH2:21][CH3:22])[CH2:23][CH3:24])[CH3:25].[CH3:1][C:2]([CH3:3])([CH3:4])[CH:5]([C:6](=[O:7])[O-:8])[c:9]1[n:10][c:11]([C:15]([F:16])([F:17])[F:18])[cH:12][cH:13][cH:14]1.[Cl:33][CH2:34][Cl:35].[F:26][C:27]([F:28])([F:29])[C:30]([OH:31])=[O:32]>>[CH2:5]([C:6](=[O:7])[OH:8])[c:9]1[n:10][c:11]([C:15]([F:16])([F:17])[F:18])[cH:12][cH:13][cH:14]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 12052TriethylsilaneHCID 867621751,1-Dimethylethyl[6-(trifluoromethyl)-2-pyridinyl]acetate

Product 1

HCID 534015132-(6-(Trifluoromethyl)pyridin-2-yl)acetic acid

Sources & evidence

ORD record
ord-b94a6453150b40d8abee040493e97d20
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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