Dichloromethane → Isopropyl 4-Hydroxypiperidine-1-carboxylate

HRID 665868Notes

Reaction equation

HRID 665868 reaction equation
[CH:8]([N:9]([CH2:10][CH3:11])[CH:12]([CH3:13])[CH3:14])([CH3:15])[CH3:16].[Cl:17][C:18](=[O:19])[O:20][CH:21]([CH3:22])[CH3:23].[Cl:24][CH2:25][Cl:26].[OH:1][CH:2]1[CH2:3][CH2:4][NH:5][CH2:6][CH2:7]1>>[OH:1][CH:2]1[CH2:3][CH2:4][N:5]([C:18](=[O:19])[O:20][CH:21]([CH3:22])[CH3:23])[CH2:6][CH2:7]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 7917Isopropyl chloroformateHCID 79341Piperidin-4-olHCID 81531Diisopropylethylamine

Product 1

HCID 16745126Isopropyl 4-Hydroxypiperidine-1-carboxylate

Sources & evidence

ORD record
ord-356248e2cb624758bc2752e3c0cca73b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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