Hydrochloric Acid → 2-[4-(2-Cyclopentyl-4,6-dioxo-tetrahydro-pyran-2-ylmethoxy)-2-fluoro-phenyl]-2-methyl-propionitrile
Reaction equation
[C:3]([CH2:4][C:5](=[O:6])[CH3:7])(=[O:8])[O:9][CH3:10].[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[CH3:11][CH2:12][CH2:13][CH2:14][Li:15].[CH:16]1([C:21]([CH2:22][O:23][c:24]2[cH:25][c:26]([F:35])[c:27]([C:30]([C:31]#[N:32])([CH3:33])[CH3:34])[cH:28][cH:29]2)=[O:36])[CH2:17][CH2:18][CH2:19][CH2:20]1.[ClH:37].[H-:1].[Na+:2]>>[C:3]1(=[O:8])[CH2:4][C:5](=[O:6])[CH2:7][C:21]([CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20]2)([CH2:22][O:23][c:24]2[cH:25][c:26]([F:35])[c:27]([C:30]([C:31]#[N:32])([CH3:33])[CH3:34])[cH:28][cH:29]2)[O:36]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-5d478de6e21049479673f9b4e71d4b7c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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