Hydrochloric Acid → 3-[4-[2-[2-(Trifluoromethyl)phenyl]acetyl]piperidino]methyl-1H-pyrazin-2-one
Reaction equation
[C:1]([O:2][CH2:3][CH3:4])(=[O:5])[CH3:6].[C:8]([CH3:9])([CH3:10])([CH3:11])[O:12][c:13]1[c:14]([CH2:19][N:20]2[CH2:21][CH2:22][CH:23]([C:26]([CH2:27][c:28]3[c:29]([C:34]([F:35])([F:36])[F:37])[cH:30][cH:31][cH:32][cH:33]3)=[O:38])[CH2:24][CH2:25]2)[n:15][cH:16][cH:17][n:18]1.[Cl:41][CH2:42][Cl:43].[ClH:7].[Na+:40].[OH-:39]>>[O:12]=[c:13]1[c:14]([CH2:19][N:20]2[CH2:21][CH2:22][CH:23]([C:26]([CH2:27][c:28]3[c:29]([C:34]([F:35])([F:36])[F:37])[cH:30][cH:31][cH:32][cH:33]3)=[O:38])[CH2:24][CH2:25]2)[n:15][cH:16][cH:17][nH:18]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-d903f054fd384dd7ae1dc9da49b8dff5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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