Potassium Cation → N-[[1-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichlorophenyl]pyrrol-2-yl]methyl]-3-[6-(2-pyridin-4-ylethenyl)-3-pyridinyl]prop-2-enamide

HRID 667849Notes

Reaction equation

HRID 667849 reaction equation
[Br:41][c:42]1[c:43]([CH3:52])[n:44][c:45]2[n:46]1[cH:47][cH:48][cH:49][c:50]2[OH:51].[C:53](=[O:54])([O-:55])[O-:56].[CH3:36][S:37](=[O:38])(=[O:39])[Cl:40].[CH3:59][N:60]([CH3:61])[CH:62]=[O:63].[CH3:65][CH2:66][N:67]([CH2:68][CH3:69])[CH2:70][CH3:71].[Cl:1][c:2]1[c:3](-[n:11]2[c:12]([CH2:16][NH:17][C:18]([CH:19]=[CH:20][c:21]3[cH:22][n:23][c:24]([CH:27]=[CH:28][c:29]4[cH:30][cH:31][n:32][cH:33][cH:34]4)[cH:25][cH:26]3)=[O:35])[cH:13][cH:14][cH:15]2)[cH:4][cH:5][c:6]([Cl:10])[c:7]1[CH2:8][OH:9].[K+:57].[K+:58].[OH2:64]>>[Cl:1][c:2]1[c:3](-[n:11]2[c:12]([CH2:16][NH:17][C:18]([CH:19]=[CH:20][c:21]3[cH:22][n:23][c:24]([CH:27]=[CH:28][c:29]4[cH:30][cH:31][n:32][cH:33][cH:34]4)[cH:25][cH:26]3)=[O:35])[cH:13][cH:14][cH:15]2)[cH:4][cH:5][c:6]([Cl:10])[c:7]1[CH2:8][O:9][c:50]1[c:45]2[n:44][c:43]([CH3:52])[c:42]([Br:41])[n:46]2[cH:47][cH:48][cH:49]1

Participants

9

Reactant 8

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 8471TriethylamineHCID 19660Carbonate IonHCID 31297Methanesulfonyl chlorideHCID 183219553-Bromo-8-hydroxy-2-methylimidazo[1,2-a]pyridineHCID 53785248N-[[1-[2,4-dichloro-3-(hydroxymethyl)phenyl]pyrrol-2-yl]methyl]-3-[6-(2-pyridin-4-ylethenyl)-3-pyridinyl]prop-2-enamide

Product 1

HCID 53830145N-[[1-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichlorophenyl]pyrrol-2-yl]methyl]-3-[6-(2-pyridin-4-ylethenyl)-3-pyridinyl]prop-2-enamide

Sources & evidence

ORD record
ord-28a1b4e4a1f6413c8dc063d4a726dc83
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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