Piperazine → 2-(4-Chloro-5-methyl-3-trifluoromethyl-pyrazol-1-yl)-1-[4-(4-chloro-phenyl)-4-(piperazine-1-carbonyl)-piperidin-1-yl]-ethanone
Reaction equation
[CH2:31]1[CH2:32][NH:33][CH2:34][CH2:35][NH:36]1.[CH3:37][N:38]1[CH2:39][CH2:40][CH2:41][C:42]1=[O:43].[Cl:1][c:2]1[c:3]([C:27]([F:28])([F:29])[F:30])[n:4][n:5]([CH2:8][C:9](=[O:10])[N:11]2[CH2:12][CH2:13][C:14]([C:17](=[O:18])[OH:19])([c:20]3[cH:21][cH:22][c:23]([Cl:26])[cH:24][cH:25]3)[CH2:15][CH2:16]2)[c:6]1[CH3:7]>>[Cl:1][c:2]1[c:3]([C:27]([F:28])([F:29])[F:30])[n:4][n:5]([CH2:8][C:9](=[O:10])[N:11]2[CH2:12][CH2:13][C:14]([C:17](=[O:18])[N:33]3[CH2:32][CH2:31][NH:36][CH2:35][CH2:34]3)([c:20]3[cH:21][cH:22][c:23]([Cl:26])[cH:24][cH:25]3)[CH2:15][CH2:16]2)[c:6]1[CH3:7]Participants
4
Sources & evidence
- ORD record
- ord-b8dc874623814d71b9b0473540cd1b43
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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