Hydrochloric Acid → (+/-)-N-[1-[2-(phenylmethyl)-4-piperidinyl]-4-phenyl-4-piperidinyl]acetamide

HRID 669398Notes

Reaction equation

HRID 669398 reaction equation
[C:1]([CH3:2])(=[O:3])[NH:4][C:5]1([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[CH2:6][CH2:7][N:8]([CH:11]2[CH2:12][CH:13]([CH2:24][c:25]3[cH:26][cH:27][cH:28][cH:29][cH:30]3)[N:14]([C:17]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[CH2:15][CH2:16]2)[CH2:9][CH2:10]1.[CH3:37][OH:38].[CH3:39][CH:40]([OH:41])[CH3:42].[ClH:43]>>[C:1]([CH3:2])(=[O:3])[NH:4][C:5]1([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[CH2:6][CH2:7][N:8]([CH:11]2[CH2:12][CH:13]([CH2:24][c:25]3[cH:26][cH:27][cH:28][cH:29][cH:30]3)[NH:14][CH2:15][CH2:16]2)[CH2:9][CH2:10]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 3776IsopropanolHCID 18319927(+/-)-1,1-Dimethylethyl 4-[4-(acetylamino)-4-phenyl-1-piperidinyl]-2-(phenylmethyl)-1-piperidinecarboxylate

Product 1

HCID 18319904(+/-)-N-[1-[2-(phenylmethyl)-4-piperidinyl]-4-phenyl-4-piperidinyl]acetamide

Sources & evidence

ORD record
ord-56fb79fe30fb4fddb45ebf51a4880903
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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