Hydrochloric Acid → 1-{2-Amino-6-[(1-{7-(2-chloro-4-fluorophenyl)-2-[1-(propan-2-yl)piperidin-4-yl][1,2,4]-triazolo[1,5-c]pyrimidin-5-yl}piperidin-3-yl)amino]pyridin-3-yl}-2,2,2-trifluoroethanone
Reaction equation
[CH3:59][S:60]([CH3:61])=[O:62].[CH:50]([N:51]([CH2:52][CH3:53])[CH:54]([CH3:55])[CH3:56])([CH3:57])[CH3:58].[Cl:2][c:3]1[n:4][c:5](-[c:21]2[c:22]([Cl:28])[cH:23][c:24]([F:27])[cH:25][cH:26]2)[cH:6][c:7]2[n:8]1[n:9][c:10]([CH:12]1[CH2:13][CH2:14][N:15]([CH:18]([CH3:19])[CH3:20])[CH2:16][CH2:17]1)[n:11]2.[ClH:1].[ClH:29].[NH2:30][c:31]1[n:32][c:33]([NH:43][CH:44]2[CH2:45][NH:46][CH2:47][CH2:48][CH2:49]2)[cH:34][cH:35][c:36]1[C:37]([C:38]([F:39])([F:40])[F:41])=[O:42]>>[c:3]1([N:46]2[CH2:45][CH:44]([NH:43][c:33]3[n:32][c:31]([NH2:30])[c:36]([C:37]([C:38]([F:39])([F:40])[F:41])=[O:42])[cH:35][cH:34]3)[CH2:49][CH2:48][CH2:47]2)[n:4][c:5](-[c:21]2[c:22]([Cl:28])[cH:23][c:24]([F:27])[cH:25][cH:26]2)[cH:6][c:7]2[n:8]1[n:9][c:10]([CH:12]1[CH2:13][CH2:14][N:15]([CH:18]([CH3:19])[CH3:20])[CH2:16][CH2:17]1)[n:11]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-d3fa8a2d2b944690988698ab58aa83f9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…