Dichloromethane → HCID 178442299, compound

HRID 669739Notes

Reaction equation

HRID 669739 reaction equation
[CH:39]([N:40]([CH2:41][CH3:42])[CH:43]([CH3:44])[CH3:45])([CH3:46])[CH3:47].[Cl:1][c:2]1[c:3]([F:31])[c:4]([CH:8]2[CH:9]([C:28](=[O:29])[OH:30])[NH:10][CH:11]([CH2:23][C:24]([CH3:25])([CH3:26])[CH3:27])[C:12]2([C:13]#[N:14])[c:15]2[c:16]([F:22])[cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[cH:5][cH:6][cH:7]1.[Cl:76][CH2:77][Cl:78].[F:32][C:33]([F:34])([F:35])[C:36]([OH:37])=[O:38].[I:63][c:64]1[cH:65][c:66]([O:71][C:72]([F:73])([F:74])[F:75])[c:67]([NH2:68])[cH:69][cH:70]1.[c:48]1([P:49]([Cl:50])([c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)=[O:57])[cH:58][cH:59][cH:60][cH:61][cH:62]1>>[Cl:1][c:2]1[c:3]([F:31])[c:4]([CH:8]2[CH:9]([C:28](=[O:29])[NH:68][c:67]3[c:66]([O:71][C:72]([F:73])([F:74])[F:75])[cH:65][c:64]([I:63])[cH:70][cH:69]3)[NH:10][CH:11]([CH2:23][C:24]([CH3:25])([CH3:26])[CH3:27])[C:12]2([C:13]#[N:14])[c:15]2[c:16]([F:22])[cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[cH:5][cH:6][cH:7]1

Participants

7

Reactant 6

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 73910Diphenylphosphinic chlorideHCID 81531DiisopropylethylamineHCID 27613984-Iodo-2-(trifluoromethoxy)anilineHCID 666882513-(3-Chloro-2-fluoro-phenyl)-4-(4-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carboxylic acid

Product 1

HCID 178442299HCID 178442299, compound

Sources & evidence

ORD record
ord-52d4b02cc26f47fa8115c60228d58410
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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