Citric Acid → 3-[2-[tert-butyl(diphenyl)silyl]oxyethoxy]-2-[1-(2,6-dichlorophenyl)pyrazolo[5,4-d]pyrimidin-4-yl]oxy-N-(5-fluoro-2-pyridinyl)propanamide
Reaction equation
[C:3]([CH3:4])([CH3:5])([CH3:6])[Si:7]([O:8][CH2:9][CH2:10][O:11][CH2:12][CH:13]([C:14](=[O:15])[NH:16][c:17]1[n:18][cH:19][c:20]([F:23])[cH:21][cH:22]1)[OH:24])([c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1)[c:31]1[cH:32][cH:33][cH:34][cH:35][cH:36]1.[CH2:68]1[O:69][CH2:70][CH2:71][CH2:72]1.[CH3:74][CH2:75][O:76][C:77]([CH3:78])=[O:79].[Cl:37][c:38]1[c:39]2[c:40]([n:41][cH:42][n:43]1)[n:44](-[c:47]1[c:48]([Cl:54])[cH:49][cH:50][cH:51][c:52]1[Cl:53])[n:45][cH:46]2.[H-:1].[Na+:2].[OH2:73].[OH:55][C:56]([CH2:57][C:58]([C:59](=[O:60])[OH:61])([CH2:62][C:63](=[O:64])[OH:65])[OH:66])=[O:67]>>[C:3]([CH3:4])([CH3:5])([CH3:6])[Si:7]([O:8][CH2:9][CH2:10][O:11][CH2:12][CH:13]([C:14](=[O:15])[NH:16][c:17]1[n:18][cH:19][c:20]([F:23])[cH:21][cH:22]1)[O:24][c:38]1[c:39]2[c:40]([n:41][cH:42][n:43]1)[n:44](-[c:47]1[c:48]([Cl:54])[cH:49][cH:50][cH:51][c:52]1[Cl:53])[n:45][cH:46]2)([c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1)[c:31]1[cH:32][cH:33][cH:34][cH:35][cH:36]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-94c1cd6627cf44baacf03c2290d4d398
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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