Tetrahydrofuran → 2-(5-amino-7-bromo-3-chloro-1-fluoro-5H-chromeno[2,3-c]pyridin-5-yl)ethanol
Reaction equation
[Al+3:2].[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3].[N:7](=[N+:8]=[N-:9])[C:10]1([CH2:27][CH2:28][OH:29])[c:11]2[cH:12][c:13]([Br:26])[cH:14][cH:15][c:16]2[O:17][c:18]2[c:19]([F:25])[n:20][c:21]([Cl:24])[cH:22][c:23]21>>[NH2:7][C:10]1([CH2:27][CH2:28][OH:29])[c:11]2[cH:12][c:13]([Br:26])[cH:14][cH:15][c:16]2[O:17][c:18]2[c:19]([F:25])[n:20][c:21]([Cl:24])[cH:22][c:23]21Participants
6
Sources & evidence
- ORD record
- ord-26a89997547a41bb952530c9ae588f0e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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