Ammonium → 6-chloro-N-methyl-4-o-tolyl-nicotinamide

HRID 671401Notes

Reaction equation

HRID 671401 reaction equation
[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[Cl-:12].[Cl-:21].[Cl:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[NH:8][CH3:9])[cH:10][cH:11]1.[K+:28].[Mn:23]([O-:24])(=[O:25])(=[O:26])=[O:27].[NH4+:22].[c:13]1([CH3:20])[c:14]([Mg+:19])[cH:15][cH:16][cH:17][cH:18]1>>[Cl:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[NH:8][CH3:9])[c:10](-[c:14]2[c:13]([CH3:20])[cH:18][cH:17][cH:16][cH:15]2)[cH:11]1

Participants

8

Reactant 7

HCID 223AmmoniumHCID 312Chloride2×HCID 813Potassium CationHCID 8028TetrahydrofuranHCID 24401PermanganateHCID 123642306-Chloro-N-methylnicotinamideHCID 178424302HCID 178424302, compound

Product 1

HCID 121673126-chloro-N-methyl-4-o-tolyl-nicotinamide

Sources & evidence

ORD record
ord-c4915f2eaeae43f2b152240fc206e083
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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