N-methyl-2-pyrrolidone → 1-(3-(2-(4-(1H-benzo[d]imidazole-2-carbonyl)phenoxy)pyridin-3-yl)pyrrolidin-1-yl)ethanone

HRID 672329Notes

Reaction equation

HRID 672329 reaction equation
[C:34](=[O:35])([O-:36])[O-:37].[CH3:42][N:43]1[CH2:44][CH2:45][CH2:46][C:47]1=[O:48].[Cs+:38].[Cs+:39].[Cu:40][I:41].[F:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1[CH:8]1[CH2:9][N:10]([C:13]([CH3:14])=[O:15])[CH2:11][CH2:12]1.[nH:16]1[c:17]([C:25](=[O:26])[c:27]2[cH:28][cH:29][c:30]([OH:33])[cH:31][cH:32]2)[n:18][c:19]2[c:20]1[cH:21][cH:22][cH:23][cH:24]2>>[c:2]1([O:33][c:30]2[cH:29][cH:28][c:27]([C:25]([c:17]3[nH:16][c:20]4[c:19]([n:18]3)[cH:24][cH:23][cH:22][cH:21]4)=[O:26])[cH:32][cH:31]2)[n:3][cH:4][cH:5][cH:6][c:7]1[CH:8]1[CH2:9][N:10]([C:13]([CH3:14])=[O:15])[CH2:11][CH2:12]1

Participants

7

Reactant 6

HCID 13387N-methyl-2-pyrrolidoneHCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 104967Cesium cation2×HCID 59326874(1H-benzo[d]imidazol-2-yl)(4-hydroxyphenyl)methanoneHCID 593272171-(3-(2-Fluoropyridin-3-yl)pyrrolidin-1-yl)ethanone

Product 1

HCID 593270971-(3-(2-(4-(1H-benzo[d]imidazole-2-carbonyl)phenoxy)pyridin-3-yl)pyrrolidin-1-yl)ethanone

Sources & evidence

ORD record
ord-596713cc78354ae79546f94cd24c3642
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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