反应详情

A solution of 3.42 g. of 2,3,5,6,7,8-hexahydro-2,3-diphenylthiazolo[3,2-a][1,3]diazepin-3-ol, prepared as described in Example 4, in acetone is treated with a solution of 1.50 g. of L-tartaric acid in acetone. Isopropanol is added and the mixture is warmed briefly to dissolve the gum which forms. After cooling, the solid is collected and recrystallized from a mixture of methanol and isopropanol, giving 3.15 g. of the desired product, m.p. 138°-140° C.

1. additionis treated with a solution of 1.50 g
2. temperaturethe mixture is warmed briefly
3. dissolutionto dissolve the gum which
4. temperatureAfter cooling
5. customthe solid is collected
6. customrecrystallized from a mixture of methanol and isopropanol
7. customgiving 3.15 g