Triethylamine → 4-[(4-Methyl-1H-indol-5-yl)amino]-5-(1,3-thiazol-2-yl)nicotinonitrile
Reaction equation
[CH2:21]([Sn:22]([CH2:23][CH2:24][CH2:25][CH3:31])([c:26]1[s:27][cH:28][cH:29][n:30]1)[CH2:32][CH2:33][CH2:34][CH3:35])[CH2:36][CH2:37][CH3:38].[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[I:1][c:2]1[cH:3][n:4][cH:5][c:6]([C:7]#[N:8])[c:9]1[NH:10][c:11]1[c:12]([CH3:20])[c:13]2[cH:14][cH:15][nH:16][c:17]2[cH:18][cH:19]1.[O:46]1[CH2:47][CH2:48][O:49][CH2:50][CH2:51]1.[Pd:52]([Cl:53])[Cl:54].[c:55]1([P:56]([c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)[c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)[cH:69][cH:70][cH:71][cH:72][cH:73]1.[c:74]1([P:75]([c:76]2[cH:77][cH:78][cH:79][cH:80][cH:81]2)[c:82]2[cH:83][cH:84][cH:85][cH:86][cH:87]2)[cH:88][cH:89][cH:90][cH:91][cH:92]1>>[c:2]1(-[c:26]2[s:27][cH:28][cH:29][n:30]2)[cH:3][n:4][cH:5][c:6]([C:7]#[N:8])[c:9]1[NH:10][c:11]1[c:12]([CH3:20])[c:13]2[cH:14][cH:15][nH:16][c:17]2[cH:18][cH:19]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-b89b8aaa7ca741bba5a6fb62f6706f72
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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