Bicarbonate Ion → tert-Butyl 2-chloro-6-vinylisonicotinate

HRID 672555Notes

Reaction equation

HRID 672555 reaction equation
[C:23](=[O:24])([OH:25])[O-:26].[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1.[CH3:16][CH2:17][N:18]([CH2:19][CH3:20])[CH2:21][CH3:22].[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[O:7][C:8]([CH3:9])([CH3:10])[CH3:11])[cH:12][c:13]([Cl:15])[n:14]1.[Na+:27]>>[c:2]1([CH:16]=[CH2:17])[cH:3][c:4]([C:5](=[O:6])[O:7][C:8]([CH3:9])([CH3:10])[CH3:11])[cH:12][c:13]([Cl:15])[n:14]1

Participants

6

Reactant 5

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 22594123tert-Butyl 2,6-dichloropyridine-4-carboxylate

Product 1

HCID 86657031tert-Butyl 2-chloro-6-vinylisonicotinate

Sources & evidence

ORD record
ord-eabb941ce1f747d49cd4e5fc074c11e7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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