Hydrochloric Acid → 4-fluoro-2-(4-fluorophenyl)-5-(4-methoxy-2-methyl-5-(3-(pyrimidin-2-yl)oxetan-3-ylcarbamoyl)phenyl)-N-methylbenzofuran-3-carboxamide
Reaction equation
[CH3:79][CH2:80][N:81]([CH2:82][CH3:83])[CH2:84][CH3:85].[ClH:34].[F:1][c:2]1[c:3](-[c:22]2[c:23]([CH3:33])[cH:24][c:25]([O:31][CH3:32])[c:26]([C:27](=[O:28])[OH:29])[cH:30]2)[cH:4][cH:5][c:6]2[c:7]1[c:8]([C:18]([NH:19][CH3:20])=[O:21])[c:9](-[c:11]1[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]1)[o:10]2.[OH2:86].[P-:46]([F:47])([F:48])([F:49])([F:50])([F:51])[F:52].[n:35]1[c:36]([C:41]2([NH2:45])[CH2:42][O:43][CH2:44]2)[n:37][cH:38][cH:39][cH:40]1.[n:53]1([O:54][P+:55]([N:56]2[CH2:57][CH2:58][CH2:59][CH2:60]2)([N:61]2[CH2:62][CH2:63][CH2:64][CH2:65]2)[N:66]2[CH2:67][CH2:68][CH2:69][CH2:70]2)[c:71]2[cH:72][cH:73][cH:74][cH:75][c:76]2[n:77][n:78]1>>[F:1][c:2]1[c:3](-[c:22]2[c:23]([CH3:33])[cH:24][c:25]([O:31][CH3:32])[c:26]([C:27](=[O:28])[NH:45][C:41]3([c:36]4[n:35][cH:40][cH:39][cH:38][n:37]4)[CH2:42][O:43][CH2:44]3)[cH:30]2)[cH:4][cH:5][c:6]2[c:7]1[c:8]([C:18]([NH:19][CH3:20])=[O:21])[c:9](-[c:11]1[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]1)[o:10]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-283af82adf76464f91b43c4bc948198a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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