1,2-Dichloroethane → 3-{5-amino-4-[3-(4-methyl-piperazin-1-ylmethyl)-benzoyl]-pyrazol-1-yl}-N-cyclopropyl-4-methyl-benzamide
Reaction equation
[C:37]([OH:38])(=[O:39])[CH3:40].[CH3:30][N:31]1[CH2:32][CH2:33][NH:34][CH2:35][CH2:36]1.[Cl:43][CH2:44][Cl:45].[Cl:46][CH2:47][CH2:48][Cl:49].[NH2:1][c:2]1[c:3]([C:20]([c:21]2[cH:22][c:23]([CH:27]=[O:28])[cH:24][cH:25][cH:26]2)=[O:29])[cH:4][n:5][n:6]1-[c:7]1[cH:8][c:9]([C:10](=[O:11])[NH:12][CH:13]2[CH2:14][CH2:15]2)[cH:16][cH:17][c:18]1[CH3:19].[Na+:42].[OH-:41]>>[NH2:1][c:2]1[c:3]([C:20]([c:21]2[cH:22][c:23]([CH2:27][N:34]3[CH2:33][CH2:32][N:31]([CH3:30])[CH2:36][CH2:35]3)[cH:24][cH:25][cH:26]2)=[O:29])[cH:4][n:5][n:6]1-[c:7]1[cH:8][c:9]([C:10](=[O:11])[NH:12][CH:13]2[CH2:14][CH2:15]2)[cH:16][cH:17][c:18]1[CH3:19]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-105887de15b24ca0bf4686a908c9d172
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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