Ammonia → 4-(4-Fluorophenyl)-2-Bromo-1-(3-Phenylpropyl)-5-(4-Pyridyl)-Imidazole

HRID 673022Notes

Reaction equation

HRID 673022 reaction equation
[Br:6][Br:7].[CH3:41][CH2:42][O:43][C:44](=[O:45])[CH3:46].[NH3:40].[P:1]([Cl:2])([Cl:3])([Cl:4])=[O:5].[P:8]([Br:9])([Br:10])[Br:11].[c:12]1([CH2:18][CH2:19][CH2:20][n:21]2[c:22](=[O:39])[nH:23][c:24](-[c:32]3[cH:33][cH:34][c:35]([F:38])[cH:36][cH:37]3)[c:25]2-[c:26]2[cH:27][cH:28][n:29][cH:30][cH:31]2)[cH:13][cH:14][cH:15][cH:16][cH:17]1>>[Br:6][c:22]1[n:21]([CH2:20][CH2:19][CH2:18][c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[c:25](-[c:26]2[cH:27][cH:28][n:29][cH:30][cH:31]2)[c:24](-[c:32]2[cH:33][cH:34][c:35]([F:38])[cH:36][cH:37]2)[n:23]1

Participants

7

Reactant 6

HCID 222AmmoniaHCID 8857Ethyl AcetateHCID 24408BromineHCID 24614Phosphorus tribromideHCID 24813Phosphorus oxychlorideHCID 113262601,3-Dihydro-1-(3-phenylpropyl)-4-(4-fluorophenyl)-5-(4-pyridyl)-imidazol-2-one

Product 1

HCID 113395554-(4-Fluorophenyl)-2-Bromo-1-(3-Phenylpropyl)-5-(4-Pyridyl)-Imidazole

Sources & evidence

ORD record
ord-808213727b984fa2aca15a687e10ec52
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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