Dimethylformamide → 3-[2-(2-Chloro-3,6-difluoro-phenyl)-acetylamino]-pyrazine-2-carboxylic acid methyl ester
Reaction equation
[CH3:20][N:21]([CH3:22])[CH:23]=[O:24].[CH3:25][O:26][C:27](=[O:28])[c:29]1[n:30][cH:31][cH:32][n:33][c:34]1[NH2:35].[CH3:39][C:40]#[N:41].[Cl:1][C:2]([C:3]([Cl:4])=[O:5])=[O:6].[Cl:36][CH2:37][Cl:38].[Cl:7][c:8]1[c:9]([CH2:16][C:17](=[O:18])[OH:19])[c:10]([F:15])[cH:11][cH:12][c:13]1[F:14]>>[Cl:7][c:8]1[c:9]([CH2:16][C:17](=[O:19])[NH:35][c:34]2[c:29]([C:27]([O:26][CH3:25])=[O:28])[n:30][cH:31][cH:32][n:33]2)[c:10]([F:15])[cH:11][cH:12][c:13]1[F:14]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-229462ddb8ab43469b8538f7e681b121
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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