Tetrahydrofuran → Ethyl 3-cyano-2,2-bis(4-fluorophenyl)propanoate
Reaction equation
[Br:31][CH2:32][C:33]#[N:34].[CH3:21][Si:22]([N-:23][Si:24]([CH3:25])([CH3:26])[CH3:27])([CH3:28])[CH3:29].[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([C:9](=[O:10])[O:11][CH2:12][CH3:13])[c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)[cH:6][cH:7]1.[Li+:30].[O:35]1[CH2:36][CH2:37][CH2:38][CH2:39]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]([C:9](=[O:10])[O:11][CH2:12][CH3:13])([c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)[CH2:32][C:33]#[N:34])[cH:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-bb2ca7e9a76546ef92e6f9952e3828f0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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