Dichloromethane → N-(3,3-dimethylbutyl)-2-(2'-oxo-5,6-dihydrospiro[benzo[1,2-b:5,4-b']difuran-3,3'-indol]-1'(2'H)-yl)acetamide

HRID 673438Notes

Reaction equation

HRID 673438 reaction equation
[CH2:26]([O:27][C:28]([Cl:29])=[O:30])[CH:31]([CH3:32])[CH3:33].[CH3:34][N:35]1[CH2:36][CH2:37][O:38][CH2:39][CH2:40]1.[CH3:41][C:42]([CH2:43][CH2:44][NH2:45])([CH3:46])[CH3:47].[Cl:48][CH2:49][Cl:50].[O:1]=[C:2]1[N:3]([CH2:22][C:23](=[O:24])[OH:25])[c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[C:10]12[c:11]1[c:12]([cH:15][c:16]3[c:20]([cH:21]1)[CH2:19][CH2:18][O:17]3)[O:13][CH2:14]2>>[O:1]=[C:2]1[N:3]([CH2:22][C:23](=[O:24])[NH:45][CH2:44][CH2:43][C:42]([CH3:41])([CH3:46])[CH3:47])[c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[C:10]12[c:11]1[c:12]([cH:15][c:16]3[c:20]([cH:21]1)[CH2:19][CH2:18][O:17]3)[O:13][CH2:14]2

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 79724-MethylmorpholineHCID 197093,3-DimethylbutylamineHCID 62365Isobutyl chloroformateHCID 59263485(2'-oxo-5,6-dihydrospiro[benzo[1,2-b:5,4-b']difuran-3,3-indol]-1'(2'H)-yl)acetic acid

Product 1

HCID 59352706N-(3,3-dimethylbutyl)-2-(2'-oxo-5,6-dihydrospiro[benzo[1,2-b:5,4-b']difuran-3,3'-indol]-1'(2'H)-yl)acetamide

Sources & evidence

ORD record
ord-2f43f88b5dff45d7a0cb353ff0bf382f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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