Dimethylformamide → N1-Ethyl-5-(2-(piperidin-1-ylcarbonyl)amino-4-pyridyl)oxy-1H-1-indolecarboxamide

HRID 673532Notes

Reaction equation

HRID 673532 reaction equation
[CH2:1]1[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1.[CH2:38]([CH3:39])[NH:40][C:41](=[O:42])[n:43]1[cH:44][cH:45][c:46]2[cH:47][c:48]([O:52][c:53]3[cH:54][c:55]([NH:59][C:60](=[O:61])[N:62]4[CH2:63][CH2:64][CH:65]([N:68]5[CH2:69][CH2:70][CH2:71][CH2:72]5)[CH2:66][CH2:67]4)[n:56][cH:57][cH:58]3)[cH:49][cH:50][c:51]12.[CH2:7]([NH:8][C:9]([n:10]1[c:11]2[c:12]([cH:13][c:14]([O:15][c:16]3[cH:17][cH:18][n:19][c:20]([NH:21][C:22](=[O:23])[O:24][c:25]4[cH:26][cH:27][cH:28][cH:29][cH:30]4)[cH:31]3)[cH:32][cH:33]2)[cH:34][cH:35]1)=[O:36])[CH3:37].[CH3:73][N:74]([CH3:75])[CH:76]=[O:77]>>[CH2:38]([CH3:39])[NH:40][C:41](=[O:42])[n:43]1[cH:44][cH:45][c:46]2[cH:47][c:48]([O:52][c:53]3[cH:54][c:55]([NH:59][C:60](=[O:61])[N:62]4[CH2:63][CH2:64][CH2:65][CH2:66][CH2:67]4)[n:56][cH:57][cH:58]3)[cH:49][cH:50][c:51]12

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 8082PiperidineHCID 9982436N1-Ethyl-5-(2-(((4-(pyrrolidin-1-yl)piperidin-1-yl)carbonyl)amino)pyridin-4-yloxy)-1H-1-indolecarboxamideHCID 21949099Phenyl N-(4-(1-(ethylamino)carbonyl-1H-5-indolyl)oxy-2-pyridyl)carbamate

Product 1

HCID 10409125N1-Ethyl-5-(2-(piperidin-1-ylcarbonyl)amino-4-pyridyl)oxy-1H-1-indolecarboxamide

Sources & evidence

ORD record
ord-38fddefc0b754af8a11fdb1317784a49
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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