HRID673901

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8028

Tetrahydrofuran

C4H8O

HCID68263

1,1'-Carbonyldiimidazole

C7H6N4O

HCID5142091

O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine

C5H11NO2

HCID25181547

Halauxifen

C13H9Cl2FN2O3

PRODUCTS

产物

HCID59471280

4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-N-(tetrahydro-2H-pyran-2-yloxy)picolinamide

C18H18Cl2FN3O4

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-56669c1c872f4992ae3856b84b0a76b3
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (3/10)

反应SMILES

[C:1]([n:2]1[cH:3][cH:4][n:5][cH:6]1)([n:7]1[cH:8][cH:9][n:10][cH:11]1)=[O:12].[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[NH2:13][c:14]1[c:15]([Cl:33])[c:16]([C:30](=[O:31])[OH:32])[n:17][c:18](-[c:20]2[c:21]([F:29])[c:22]([O:27][CH3:28])[c:23]([Cl:26])[cH:24][cH:25]2)[cH:19]1.[O:34]1[CH:35]([O:40][NH2:41])[CH2:36][CH2:37][CH2:38][CH2:39]1>>[NH2:13][c:14]1[c:15]([Cl:33])[c:16]([C:30](=[O:32])[NH:41][O:40][CH:35]2[O:34][CH2:39][CH2:38][CH2:37][CH2:36]2)[n:17][c:18](-[c:20]2[c:21]([F:29])[c:22]([O:27][CH3:28])[c:23]([Cl:26])[cH:24][cH:25]2)[cH:19]1