Dimethyl Sulfoxide → 4-[2-(Cyclohexylmethyl-amino)-benzooxazol-6-yloxy]-pyridine-2-carbonitrile

HRID 674164Notes

Reaction equation

HRID 674164 reaction equation
[CH2:38]([N:39]([CH2:40][CH3:41])[CH2:42][CH3:43])[CH3:44].[CH2:45]([Cl:46])[Cl:47].[CH3:1][S:2]([CH3:3])=[O:4].[CH:11]1([CH2:17][NH:18][c:19]2[o:20][c:21]3[c:22]([n:23]2)[cH:24][cH:25][c:26]([O:28][c:29]2[cH:30][c:31]([C:35](=[O:36])[NH2:37])[n:32][cH:33][cH:34]2)[cH:27]3)[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]1.[Cl:5][C:6]([C:7]([Cl:8])=[O:9])=[O:10]>>[CH:11]1([CH2:17][NH:18][c:19]2[o:20][c:21]3[c:22]([n:23]2)[cH:24][cH:25][c:26]([O:28][c:29]2[cH:30][c:31]([C:35]#[N:37])[n:32][cH:33][cH:34]2)[cH:27]3)[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]1

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 6344DichloromethaneHCID 8471TriethylamineHCID 65578Oxalyl chlorideHCID 57725827HCID 57725827, compound

Product 1

HCID 577257694-[2-(Cyclohexylmethyl-amino)-benzooxazol-6-yloxy]-pyridine-2-carbonitrile

Sources & evidence

ORD record
ord-f09761436cc64dd284d1c21b09a41dee
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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