Dimethylformamide → Methyl 2-[(4-bromo-2-fluorophenyl)amino]-5-chloro-1,6-dihydro-1-methyl-6-oxo-3-pyridinecarboxylate

HRID 674536Notes

Reaction equation

HRID 674536 reaction equation
[Br:1][c:2]1[cH:3][c:4]([F:21])[c:5]([NH:8][c:9]2[n:10]([CH3:20])[c:11](=[O:19])[cH:12][cH:13][c:14]2[C:15](=[O:16])[O:17][CH3:18])[cH:6][cH:7]1.[Cl:22][N:23]1[C:24](=[O:25])[CH2:26][CH2:27][C:28]1=[O:29].[O:30]=[CH:31][N:32]([CH3:33])[CH3:34]>>[Br:1][c:2]1[cH:3][c:4]([F:21])[c:5]([NH:8][c:9]2[n:10]([CH3:20])[c:11](=[O:19])[c:12]([Cl:22])[cH:13][c:14]2[C:15](=[O:16])[O:17][CH3:18])[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 31398ChlorosuccinimideHCID 66673525Methyl 2-(4-bromo-2-fluorophenylamino)-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate

Product 1

HCID 57636943Methyl 2-[(4-bromo-2-fluorophenyl)amino]-5-chloro-1,6-dihydro-1-methyl-6-oxo-3-pyridinecarboxylate

Sources & evidence

ORD record
ord-b5c1fa37f38540b5ac1590becc6f62a2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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