Acetate → [6-Chloro-4-(2-chloro-phenyl)-pyridin-3-yl]-methyl-amine

HRID 674736Notes

Reaction equation

HRID 674736 reaction equation
[CH3:46][CH2:47][O:48][C:49](=[O:50])[CH3:51].[CH3:61][O:62][CH2:63][CH2:64][O:65][CH3:66].[Cl:11][c:12]1[c:13]([B:18]([OH:19])[OH:20])[cH:14][cH:15][cH:16][cH:17]1.[Cl:1][c:2]1[cH:3][c:4]([I:10])[c:5]([NH:8][CH3:9])[cH:6][n:7]1.[Na+:40].[Na+:41].[O-:42][C:43](=[O:44])[O-:45].[O-:53][C:54]([CH3:55])=[O:56].[O-:57][C:58]([CH3:59])=[O:60].[Pd+2:52].[c:21]1([P:22]([c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[cH:35][cH:36][cH:37][cH:38][cH:39]1>>[Cl:1][c:2]1[cH:3][c:4](-[c:13]2[c:12]([Cl:11])[cH:17][cH:16][cH:15][cH:14]2)[c:5]([NH:8][CH3:9])[cH:6][n:7]1

Participants

10

Reactant 9

HCID 175Acetate2×HCID 923Sodium ion2×HCID 80711,2-DimethoxyethaneHCID 8857Ethyl AcetateHCID 11776TriphenylphosphineHCID 19660Carbonate IonHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 27343222-Chlorophenylboronic acidHCID 574434006-chloro-4-iodo-N-methylpyridin-3-amine

Product 1

HCID 23502811[6-Chloro-4-(2-chloro-phenyl)-pyridin-3-yl]-methyl-amine

Sources & evidence

ORD record
ord-91db8c9d16964668bf61e3e7a3a32246
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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