Tetrahydrofuran → 1-(2-Morpholinoethyl)-1,2,3,4-tetrahydroquinolin-6-amine

HRID 675900Notes

Reaction equation

[Al+3:22].[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[H-:21].[H-:24].[H-:25].[H-:26].[Li+:23].[NH2:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[N:8]([CH2:12][CH2:13][N:14]1[CH2:15][CH2:16][O:17][CH2:18][CH2:19]1)[C:7](=[O:20])[CH2:6][CH2:5]2>>[NH2:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[N:8]([CH2:12][CH2:13][N:14]1[CH2:15][CH2:16][O:17][CH2:18][CH2:19]1)[CH2:7][CH2:6][CH2:5]2

Participants

Reactant 5

HCID 8028Tetrahydrofuran

HCID 28486Lithium ion

HCID 104727Aluminum Cation

HCID 166653Hydride4×

HCID 434465466-amino-1-(2-morpholinoethyl)-3,4-dihydroquinolin-2(1H)-one

Product 1

HCID 284191151-(2-Morpholinoethyl)-1,2,3,4-tetrahydroquinolin-6-amine

Sources & evidence

ORD record: ord-501eed800b56486b94dfb073bcf5700e
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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