Trifluoroacetic acid → 6-(1-Methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

HRID 675948Notes

Reaction equation

HRID 675948 reaction equation
[CH2:47]1[O:48][CH2:49][CH2:50][CH2:51]1.[CH3:1][N:2]1[CH2:3][CH:4]=[C:5]([c:8]2[cH:9][cH:10][c:11]3[cH:12][cH:13][n:14]([CH:17]([CH3:18])[CH3:19])[c:15]3[cH:16]2)[CH2:6][CH2:7]1.[F:40][C:41]([F:42])([F:43])[C:44]([OH:45])=[O:46].[OH:20][C:21]1([c:22]2[cH:23][c:24]3[c:25]([cH:26][cH:27][n:28]3[CH:29]([CH3:30])[CH3:31])[cH:32][cH:33]2)[CH2:34][CH2:35][N:36]([CH3:37])[CH2:38][CH2:39]1>>[CH3:1][N:2]1[CH2:3][CH:4]=[C:5]([c:8]2[cH:9][cH:10][c:11]3[cH:12][cH:13][nH:14][c:15]3[cH:16]2)[CH2:6][CH2:7]1

Participants

5

Reactant 4

HCID 6422Trifluoroacetic acidHCID 8028TetrahydrofuranHCID 9925480HCID 9925480, compoundHCID 10131267HCID 10131267, compound

Product 1

HCID 101305596-(1-Methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

Sources & evidence

ORD record
ord-e43f8b087a1a4b418c46f7b9b967f1a3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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