2-Bromopyridine → [6-(4-Bromo-2-chloro-phenylamino)-7-fluoro-3-methyl-3H-benzoimidazol-5-yl]-pyridin-2-yl-methanol
Reaction equation
[Br:13][c:14]1[cH:15][c:16]([Cl:34])[c:17]([NH:20][c:21]2[c:22]([CH:32]=[O:33])[cH:23][c:24]3[c:25]([n:26][cH:27][n:28]3[CH3:29])[c:30]2[F:31])[cH:18][cH:19]1.[Br:1][c:2]1[cH:3][cH:4][cH:5][cH:6][n:7]1.[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:8][CH2:9][CH2:10][CH2:11][Li:12]>>[c:2]1([CH:32]([c:22]2[c:21]([NH:20][c:17]3[c:16]([Cl:34])[cH:15][c:14]([Br:13])[cH:19][cH:18]3)[c:30]([F:31])[c:25]3[c:24]([cH:23]2)[n:28]([CH3:29])[cH:27][n:26]3)[OH:33])[cH:3][cH:4][cH:5][cH:6][n:7]1Participants
5
Sources & evidence
- ORD record
- ord-13bd1522ba7e413fadb281a98d7c7f99
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…