Trifluoroacetic acid → 6-[2-[(5-Fluoro-6-methoxy-3-pyridinyl)amino]-5-[1-(4-methylsulfonylpiperazin-1-yl)ethyl]-3-pyridinyl]-2-methylpyrimidin-4-amine
Reaction equation
[F:1][c:2]1[cH:3][c:4]([NH:10][c:11]2[n:12][cH:13][c:14]([CH:43]([CH3:44])[N:45]3[CH2:46][CH2:47][N:48]([S:51](=[O:52])(=[O:53])[CH3:54])[CH2:49][CH2:50]3)[cH:15][c:16]2-[c:17]2[cH:18][c:19]([N:24]([CH2:25][c:26]3[cH:27][cH:28][c:29]([O:30][CH3:31])[cH:32][cH:33]3)[CH2:34][c:35]3[cH:36][cH:37][c:38]([O:39][CH3:40])[cH:41][cH:42]3)[n:20][c:21]([CH3:23])[n:22]2)[cH:5][n:6][c:7]1[O:8][CH3:9].[F:63][C:64]([F:65])([F:66])[C:67]([OH:68])=[O:69].[OH:55][S:56]([C:57]([F:58])([F:59])[F:60])(=[O:61])=[O:62]>>[F:1][c:2]1[cH:3][c:4]([NH:10][c:11]2[n:12][cH:13][c:14]([CH:43]([CH3:44])[N:45]3[CH2:46][CH2:47][N:48]([S:51](=[O:52])(=[O:53])[CH3:54])[CH2:49][CH2:50]3)[cH:15][c:16]2-[c:17]2[cH:18][c:19]([NH2:24])[n:20][c:21]([CH3:23])[n:22]2)[cH:5][n:6][c:7]1[O:8][CH3:9]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-a11eee1b206a47b0b51d3de62e9f57d2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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