Methane → Ethyl 4-chloro-6-hydroxy-1-methyl-2-indolecarboxylate

HRID 677449Notes

Reaction equation

HRID 677449 reaction equation
[C:30].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([Cl:24])[c:12]2[cH:13][c:14]([C:19](=[O:20])[O:21][CH2:22][CH3:23])[n:15]([CH3:18])[c:16]2[cH:17]1.[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1.[Pd:31]>>[OH:8][c:9]1[cH:10][c:11]([Cl:24])[c:12]2[cH:13][c:14]([C:19](=[O:20])[O:21][CH2:22][CH3:23])[n:15]([CH3:18])[c:16]2[cH:17]1

Participants

5

Reactant 4

HCID 297MethaneHCID 8028TetrahydrofuranHCID 23938PalladiumHCID 21194606Ethyl 6-benzyloxy-4-chloro-1-methyl-2-indolecarboxylate

Product 1

HCID 21194263Ethyl 4-chloro-6-hydroxy-1-methyl-2-indolecarboxylate

Sources & evidence

ORD record
ord-8275a24fce0447fb998cc90b7db34978
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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