Hydroxide → 1'-(trans-4-Carboxy-cyclohexylmethyl)carbamoyl-spiro[isobenzofuran-1,4'piperidin]-3-one
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[CH2:7][CH2:8][CH:9]([CH2:12][NH:13][C:14](=[O:15])[N:16]2[CH2:17][CH2:18][C:19]3([O:20][C:21](=[O:28])[c:22]4[cH:23][cH:24][cH:25][cH:26][c:27]43)[CH2:29][CH2:30]2)[CH2:10][CH2:11]1.[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[Li+:33].[OH-:32].[OH2:31].[OH2:34]>>[O:3]=[C:4]([OH:5])[CH:6]1[CH2:7][CH2:8][CH:9]([CH2:12][NH:13][C:14](=[O:15])[N:16]2[CH2:17][CH2:18][C:19]3([O:20][C:21](=[O:28])[c:22]4[cH:23][cH:24][cH:25][cH:26][c:27]43)[CH2:29][CH2:30]2)[CH2:10][CH2:11]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-fc30fcdfa0ea4a7281f7e9932df53e13
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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