1,2-Dichloroethane → HCID 178492228, compound

HRID 678441Notes

Reaction equation

HRID 678441 reaction equation
[C:27](=[O:28])([O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[N:34]1[CH:35]([C:36](=[O:37])[OH:38])[CH2:39][CH2:40][CH2:41]1.[CH2:1]([Cl:2])[CH2:3][Cl:4].[NH2:5][CH2:6][c:7]1[c:8]([CH:14]([CH:15]([F:16])[F:17])[NH:18][c:19]2[cH:20][cH:21][c:22]([O:25][CH3:26])[cH:23][cH:24]2)[cH:9][cH:10][c:11]([Cl:13])[cH:12]1.[O:42]=[CH:43][N:44]([CH3:45])[CH3:46]>>[NH:5]([CH2:6][c:7]1[c:8]([CH:14]([CH:15]([F:16])[F:17])[NH:18][c:19]2[cH:20][cH:21][c:22]([O:25][CH3:26])[cH:23][cH:24]2)[cH:9][cH:10][c:11]([Cl:13])[cH:12]1)[C:36]([CH:35]1[N:34]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[CH2:41][CH2:40][CH2:39]1)=[O:37]

Participants

5

Reactant 4

HCID 111,2-DichloroethaneHCID 6228DimethylformamideHCID 2684721-[(Tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acidHCID 18672348N-{1-[2-(aminomethyl)-4-chlorophenyl]-2,2-difluoroethyl}-N-(4-methoxyphenyl)amine

Product 1

HCID 178492228HCID 178492228, compound

Sources & evidence

ORD record
ord-175dfb72a6414528addd5674c758f331
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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