2-Aminothiazole → 3-cyclopentyl-2-[4-(3-dimethylamino-prop-1-ynyl)-phenyl]-N-thiazol-2-yl-propionamide
Reaction equation
[CH2:63]([Cl:64])[Cl:65].[CH3:50][CH2:51][N:52]([CH2:53][CH3:54])[CH2:55][CH3:56].[CH:1]1([CH2:6][CH:7]([C:8](=[O:9])[OH:10])[c:11]2[cH:12][cH:13][c:14]([C:17]#[C:18][CH2:19][N:20]([CH3:21])[CH3:22])[cH:15][cH:16]2)[CH2:2][CH2:3][CH2:4][CH2:5]1.[NH2:57][c:58]1[s:59][cH:60][cH:61][n:62]1.[P-:23]([F:24])([F:25])([F:26])([F:27])([F:28])[F:29].[n:30]1([O:31][P+:32]([N:33]([CH3:34])[CH3:35])([N:36]([CH3:37])[CH3:38])[N:39]([CH3:40])[CH3:41])[c:42]2[cH:43][cH:44][cH:45][cH:46][c:47]2[n:48][n:49]1>>[CH:1]1([CH2:6][CH:7]([C:8](=[O:10])[NH:57][c:58]2[s:59][cH:60][cH:61][n:62]2)[c:11]2[cH:12][cH:13][c:14]([C:17]#[C:18][CH2:19][N:20]([CH3:21])[CH3:22])[cH:15][cH:16]2)[CH2:2][CH2:3][CH2:4][CH2:5]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-27b32ea9fc984aaca65b5e1016f767c8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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