Hydrochloric Acid → 2-Acetylthio-3-chlorobenzoic acid

HRID 67896Notes

Reaction equation

HRID 67896 reaction equation
[Cl:1][C:2]1[C:3]([SH:11])=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5]([OH:7])=[O:6].[C:12](OC(=O)C)(=[O:14])[CH3:13].Cl>C(O)(=O)C>[C:12]([S:11][C:3]1[C:2]([Cl:1])=[CH:10][CH:9]=[CH:8][C:4]=1[C:5]([OH:7])=[O:6])(=[O:14])[CH3:13]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 7918Acetic AnhydrideHCID 131624003-Chloro-2-mercaptobenzoic acid

Product 1

HCID 134204052-Acetylthio-3-chlorobenzoic acid

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

3-Chloro-2-mercaptobenzoic acid (9.8 g, 52 mmol), acetic anhydride (6.3 g, 62 mmol) and glacial acetic acid (22 ml) were heated at 80° C. for 4 hours, then cooled and mixed with dilute hydrochloric acid.

Workup

  1. temperaturecooled

Sources & evidence

ORD record
ord-04a985bfd36648db9ebe8342f700336d
Source dataset
uspto-grants-1982_08
Patent number
US04347246

Reaction notes

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