Tetrahydrofuran → N-[4-[4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-4-oxobutan-2-yl]benzamide
Reaction equation
[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)(=[O:8])[NH:9][CH:10]([CH:11]([C:12](=[O:13])[OH:14])[CH3:15])[CH3:16].[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH:33]([N:34]([CH2:35][CH3:36])[CH:37]([CH3:38])[CH3:39])([CH3:40])[CH3:41].[Cl:17][c:18]1[cH:19][cH:20][c:21]([C:24]2([OH:32])[C:25]([CH3:30])([CH3:31])[CH2:26][NH:27][CH2:28][CH2:29]2)[cH:22][cH:23]1>>[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)(=[O:8])[NH:9][CH:10]([CH:11]([C:12](=[O:14])[N:27]1[CH2:26][C:25]([CH3:30])([CH3:31])[C:24]([c:21]2[cH:20][cH:19][c:18]([Cl:17])[cH:23][cH:22]2)([OH:32])[CH2:29][CH2:28]1)[CH3:15])[CH3:16]Participants
5
Sources & evidence
- ORD record
- ord-fbc4b32b638d4d8b92000fb0ae62a853
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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